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st comparable) depending on the dose. Fanconi anemia is a rare genetic disorder caused by mutations in genes which protein products are involved in ****tion, cell cycle control and DNA repair. It is characterized by congenital malformations, bone marrow failure, and high risk of cancer. The diagnosis is based on morphological and hematological abnormalities such as pancytopenia, macrocytic anaemia and progressive bone marrow failure. Genetic examination, often very complex, includes chromosomal breakage testing and mutational analysi
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