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We also provide evidence for the possible capability of the m5E3 antibody to disaggregate AβOs and to fragment protofilaments.Background Health literacy (HL) and patient activation (PA) are necessary foundations to engage patients in self-management intervention. Each concept plays a unique role in improving access to the effective self-management of chronic disease. In this cross-sectional study, we examined the levels and determinants of HL and PA among the multi-morbid COPD patients in Nepal. Methods We conducted interviews with a simp