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There is a need for further investigation to the characterization of the population prone to this immune-related adverse events. Even in the era of suppressive antiretroviral therapy, people with HIV (PWH) suffer greater exposure to inflammation than their uninfected peers. Although poor social support and social isolation have been linked to systemic inflammation in the general population, it is not known whether this is true also among PWH. People with and without HIV infection were enrolled in a community-based, single-center study. Pr