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125(OH)2D3 was demonstrated to negatively regulate the A-induced production of pro-inflammatory cytokines (TNF-, IL-1, and IL-6), M1 activation markers (CD86 and iNOS), and TLR2/4 expression, and positively regulate the production of anti-inflammatory cytokines (IL-4, IL-10, and CCL17) and M2 markers (CD206 and Arg-1). Moreover, 125(OH)2D3 stimulated TREM2 production and amyloid-beta uptake within HMO6 cells, and the augmented amyloid-beta uptake and M2 polarization were found to be contingent u
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