https://reversetranscriptas.co....m/index.php/fischer-
The nitration of Y214, situated near the substrate binding site, seemingly affects its association with W500. A study of protein structure 3PZW reveals multiple tunnels connecting the protein's exterior to internal cysteines, potentially enabling persulfidation, particularly in residues C429 and C127. In a contrasting manner, the CysNO molecule, exhibiting hydrophilicity and bulkiness exceeding that of H2S, is able to pass through the
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