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In the unadjusted analysis, higher VAT was associated with greater impairment in E . After adjustment for baseline risk factors, CRF, parameters of LV structure and function, and other fat depots such as SAT and LBF, higher VAT remained associated with greater impairment in E (β 0.19, P = 0.002). SAT and LBF were not significantly associated with E , however, CRF remained associated with E in the fully adjusted model including all fat depots (β -0.15, P 0.001). VAT and CRF are each independently associated with impairment in E , su
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