https://tbk1ikkin1activator.co....m/theoretical-examin
Earlier investigations have indicated a correlation between stress exposure and a reduction in the hypothalamic-pituitary-gonadal axis function, especially concerning the decrease in the neuropeptide kisspeptin (Kiss1) and its receptor (Kiss1R). While alterations in the kiss1 and Kiss1r genes were noted after the onset of puberty due to immune stress, the persistence of immune-stress-driven decreases in kiss1 and kiss1r expression
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