https://www.selleckchem.com/pr....oducts/deferoxamine-
RNA-seq data of Wnt7b-overexpressed bones uncover the significant upregulation of Sox11. Histological results further unveil that Sox11 is specifically increased in BMSCs. Wnt7b-induced Sox11 is demonstrated to reinforce both self-renewal and osteogenic differentiation of BMSCs. Mechanistically, Wnt7b activates the Ca2+ -dependent Nfatc1 signaling to directly induce Sox11 transcription, which in turn activates the transcriptions of both proliferation-related transcription factors (Ccnb1 and Sox2) and osteogenesis-related f
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