https://usp25-28inhibitoraz1.c....om/spike1-activates-
EMICs exhibited activation of the transcriptional regulators E2F1, YY1, and SMAD1. Upregulation of leukocyte immunoglobulin-like receptor subfamily B4 (LILRB4) was observed in extramedullary EMICs. The laboratory experiments confirmed that LILRB4 enhanced the motility of MM cells. The current study's findings explored the intricate evolutionary mechanisms of ME, elucidating the relationship between EMICs and LILRB4 in extrame