https://www.selleckchem.com/pr....oducts/sodium-ascorb
The electrostatic force between the negative charge at the in vitro BBB and the positive charge at NPs greatly enhances NP permeability. The predictions from our transcellular model fit very well with the measured BBB permeability for both neutral and charged NPs. Our model can be used to predict the optimal size and charge of the NPs and the optimal charge of the BBB for an optimal systemic drug delivery strategy to the brain. Our model can be used to predict the optimal size and charge of the NPs and the optimal charge of the
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