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05). In comparison with CLP group, Alp group exhibited significantly decreased concentrations of liver function markers, microscopic findings, such as decreased inflammatory cell infiltration in the interstitum, notably lowered proportion of apoptotic cells, decreased level of oxidative stress, weakened activity of the TLR4/NF-κB pathway and restrained release of TNF-α (p0.05). Furthermore, normal morphology of liver cells was observed in Alp group compared with CLP group (p0.05). Alp alleviates liver injury in septic rats by in