https://www.selleckchem.com/pr....oducts/mps1-in-6-com
The purpose of this study was to investigate the effects of miR-431-5p on hepatocyte apoptosis in AIH. We used intraperitoneal injection of S100 to establish AIH mouse model and injected AAV into tail vein on day 14 of modeling to regulate miR-431-5p expression. The expression of ALT, AST, IgG and apoptosis-related proteins Bax, Bcl-2 and cleaved caspase 3 were measured in each group. Cellular experiments were performed using miR-431-5p mimics or inhibitors to transfect LPS-stimulated AML12 cells, and apoptosis was verifie
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