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Future randomized and controlled studies are needed to confirm the results of the present multi-centrical retrospective analysis.Seven pesticides, profenofos, metalaxyl, λ-cyhalothrin, 4,4'-DDT, 4,4'-DDE, and α- and β-endosulfan, were determined in vegetables (tomato, onion) from 20 locations and surface waters from 12 locations in the Central Rift Valley (CRV) of Ethiopia. Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) and solid phase extraction (SPE) methods were used for the vegetables and water, respectively.