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Of the patients who had resective surgery, nine were Engel I or II at last follow up. We found that seizures in patients with drug resistant SRE were more frequently originated in the mesial temporal region than in the stroke lesion itself. Despite the complex epileptic network underlying drug-resistant SRE, a thorough presurgical assessment and adequate use of surgical options can lead to excellent surgical outcomes. We found that seizures in patients with drug resistant SRE were more frequently originated in the mesial temporal regio