https://www.selleckchem.com/pr....oducts/pf-477736.htm
pylori SS1, and colonization in the stomach were evaluated. Saccharomyces cerevisiae-based H.pylori oral vaccines were successfully constructed. Mice orally administered with EBY100/pYD1-UreB, EBY100/pYD1-VacA, or EBY100/pYD1-UreB+EBY100/pYD1-VacA exhibited a significant humoral immune response as well as a mucosal immune response. Importantly, S.cerevisiae-based oral vaccines could effectively reduce bacterial loads with statistical significance after H.pylori infection. Our study shows that S.cerevisiae-based platforms can serve as
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