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Following a seven-day biofilm development period, metabolic activity (MA) and biofilm characteristics were assessed using 23,5-triphenyltetrazolium chloride and Checker-board DNA-DNA hybridization, respectively. Using the Kruskal-Wallis test, followed by Dunn's post-hoc test, the statistical analysis was executed. In protocol A, all administered treatments decreased MA compared to the placebo, and this difference reached statistical significance (p0.005). Despit