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In the present study, the antioxidant activities and immunostimulatory ability of a polysaccharide extracted from Chinese Sesbania cannabina, which was identified to be a galactomannan in our previous study, were investigated. The extracted polysaccharide exhibited strong DPPH, ABTS and hydroxyl radical scavenging activities and ferrous ion chelating activity in a concentration-dependent manner. The immune-enhancing effect of our polysaccharide on RAW 264.7 macrophage cells was investigated by determining the cell viability, phagocytic