https://www.selleckchem.com/products/reversan.html
The co-administration of voriconazole (VCZ) and Wuzhi tablet (WZ) is frequently prescribed for solid organ transplantation patients in China. However, the pharmacokinetic interactions between VCZ and WZ as well as its bioactive constituents, such as schisandrin A and schisandrol B, remain unknown. Therefore, the effects of WZ and the two lignans on the metabolism of VCZ and the potential role of cytochromeP450 (CYP45, especially cytochrome P450 2C19 (CYP2C19), were investigated. The results showed that WZ extensively inhibited the ac
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