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Employing histological tissue sections of sentinel lymph nodes collected routinely from the clinical settings of a multi-center study, a deep learning method was devised. For the purpose of further review by pathologists, the algorithm was developed to mark possible melanoma metastases, while eschewing supplemental immunohistochemical stains (e.g.). Antibodies specific to S100 and Melan-A are part of this scientific inquiry. The established methodology successfully detected metastasis on individual