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3 mL/min/1.73 m /mo; 95% confidence interval [CI], -2.4 to -0.2; = 0.02) and ci + ct ≥ 3 versus 3 (coefficient -0.7 mL/min/1.73 m /mo; 95% CI, -1.3 to -0.1; = 0.03) and a trend toward significant covariate-by-time interaction for dd-cfDNA (coefficient -0.5 mL/min/1.73 m /mo; 95% CI, -1.0 to 0.1; = 0.08). Addition of acute inflammation (i, t, and v), microvascular inflammation (g and ptc), and inflammation in area of interstitial fibrosis and tubular atrophy scores to chronicity scores (cg ≥ 3 and ci + ct ≥ 3) did not improve model