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A patient, possibly exhibiting the para-Bombay phenotype, yielded blood and saliva samples for analysis. To determine the H, A, and B antigens, routine serological methods were applied to the samples. By employing Sanger sequencing, the coding regions of FUT1 and FUT2 were pinpointed. Through cloning and subsequent sequencing, the novel heterozygous mutation was definitively confirmed. Utilizing Phyre 2, a 3D model of mutant