https://www.selleckchem.com/products/vb124.html
Multipotent bone marrow-derived mesenchymal stem/ stromal cells (BMSC) exhibit a finite lifespan following ex vivo expansion leading to cellular senescence. Many factors can contribute to this. Recently, our group has identified for the first time expression of the chemokine-like factor superfamily 8 (CMTM8) gene in cultured human BMSC. In the present study, we examine the role of CMTM8 in BMSC proliferation, migration and differentiation. Functional studies using siRNA mediated knockdown of CMTM8 in human BMSC resulted in decreased capac
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