https://www.selleckchem.com/pr....oducts/8-cyclopentyl
be useful in the prediction of novel telomerase / helicase, topoisomerase and NA polymerase dependent drugs.A total of 26 compounds based on osthole skeleton were designed, synthesized. Their cytoprotective abilities of antioxidation, anti-inflammation and Aβ42(Amyloid β-protein 42)-induced neurotoxicity were evaluated by MTT assays. Mechanism of the action of selected compounds were investigated by molecular docking. AlogP, logS and blood-brain barrier (BB permeability of all these compounds were simulated
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