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Additional improvements were registered in parameters related to body weight, body mass index, body fat composition, visceral fat, blood pressure, HbA1c, and uric acid levels. Empagliflozin, liraglutide, or their combination were ineffective in inducing any improvement in arterial stiffness indexes in this research. Rigorous, impactful studies are crucial to understanding any possible influence on arterial stiffness in particular subgroups