https://www.selleckchem.com/pr....oducts/cathepsin-g-i
Hence, the cells stimulated with SiO2 responded with a distinctly different IL-18 IL-1β ratio. The difference in the IL-18 IL-1β ratio for SiO2 was constant over different doses. While all downstream responses were strictly dependent on a functional NLRP3 inflammasome, the differences did not depend on the level of gene expression, caspase-1 activity, or pyroptosis. We suggest that the NLRP3 inflammasome response should be considered a dynamic process, which can be described by taking the ratio between IL-1β and IL-18 in
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