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Sex is common among eukaryotes, but entails considerable costs. The selective conditions that drive the evolutionary maintenance of ****ual reproduction remain an open question. One long-standing explanation is that **** and recombination facilitate adaptation to fluctuating environmental conditions, although the genetic mechanisms that underlie such a benefit have not been empirically observed. In this study, we compare the dynamics and fitness effects of mutations in ****ual and a****ual diploid populations of the yeast Saccharomyces cer