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58, respectively (all p less then 0.05). Positive correlations were detected between alanine aminotransferase (ALT) and FT3 (r = 0.221, p = 0.01, and negative correlations were noted between TSH and BMR (r = -0.618, p less then 0.001) and between BMR and FT3 (r = -0.452, p less then 0.001) in T2DM subjects with NAFLD. A significant difference in serum FT3 (t = 2.468, p = 0.0167) and TSH (t = 2.658, p = 0.01 levels was found between obese individuals with NAFLD who used and did not use metformin. The pathological mechanism of T2DM c