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A remarkable 74,285,160 people were part of our study cohort. Participants medicated for depression (OR 272; 95% CI 141-524; P = 0.0009) and anxiety (OR 250; 95% CI 142-441; P = 0.0006) displayed a statistically significant correlation with a greater probability of developing hypertension. Individuals experiencing depressive feelings, both daily, monthly, and several times a year, demonstrated a higher probability of hypertension. A greater predis