https://www.selleckchem.com/pr....oducts/z-devd-fmk.ht
We also examined SLC15A4's role in autophagy response since SLC15A4 loss caused the decrease of mTORC1 activity, which greatly influences on autophagy. We found that SLC15A4 was not required for autophagy induction, but was critical for autophagy sustainability. Notably, SLC15A4-KD CAL1 severely decreased mitochondria membrane potential in the starvation condition. Our findings revealed that SLC15A4 plays a key role in mitochondria integrity in human cells, which might benefit immune cells to fulfill their functions in inflammatory m