https://www.selleckchem.com/products/Rolipram.html
The classical in vitro genotoxicity test battery is known to be sensitive for indicating genotoxicity. However, a high rate of 'misleading positives' was reported when three assays were combined as required by several legislations. Despite the recent optimizations of the standard in vitro tests, two gaps could hardly be addressed with assays based on 2D monolayer cell cultures the route of exposure and a relevant intrinsic metabolic capacity to transform pro-mutagens into reactive metabolites. Following these considerations, fertilized
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