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The impact of novel alternative accesses and valve type on radiation exposure during transcatheter aortic valve replacement (TAVR) have not been evaluated yet. This study sought to determine the impact of (i) transarterial approach and (ii) prosthesis type on physician and patient exposure to radiation during TAVR. This was a prospective study including 140 consecutive patients undergoing TAVR by transfemoral (TF) (n=102) or transcarotid (TC) (n=38) access in 2 centers. Implanted valves were the self-expanding Evolut R/PRO system (n=38) and the balloon-expa