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The purified-endolysin indicated antibacterial activity against , (sp), and . SDS-PAGE profiling followed by silica gel purification, led to introduce Lys46 as a therapeutic product and food preservative. lys46 showed antibacterial effects on the common Gram-negative pathogens in clinics and food industries; and (sp). lys4630 showed antibacterial effects on the common Gram-negative pathogens in clinics and food industries; E. coli, P. aeruginosa and Salmonella (sp). Increasing the amount of protease from microbial sources is in the focu
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