https://www.selleckchem.com/pr....oducts/oxidopamine-h
On-target/off-tumor toxicity is one of the major concerns regarding CAR T-cell therapy. Kosti et al.1 demonstrate that this form of toxicity can be prevented by designing a CAR whose expression is controlled by oxygen levels in the tumor environment.Quantifying the ****tion-competent HIV reservoir is essential for evaluating curative strategies. Viral outgrowth assays (VOAs) underestimate the reservoir because they fail to induce all ****tion-competent proviruses. Single- or double-region HIV DNA assays overestima
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