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The present study involved 22 newborns diagnosed with ductal-dependent congenital heart disease (CCHD) and receiving PGE1 infusions for a duration exceeding one week. The PGE1 infusion prompted ultrasonographic evaluations of pyloric thickness and length, a week later and initially. ClinicalTrials.gov received the protocol's registration information. The clinical trial NCT04496050. The study population comprised 22 neonates, with a mean gestational a