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ficantly better limb salvage than endovascular intervention in patients with tissue loss. Surgical options should be given more emphasis as the first-line option in this cohort of patients unless the cardiopulmonary risk is prohibitive.OCCUPATIONAL APPLICATIONS We found, contrary to expectations, that performing a fatiguing simulated heavy manual material handling (MMH) task did not adversely affect the risk of trip-induced falls when compared to a less-fatiguing light MMH task. However, when considering these MMH tasks together rather tha