https://www.selleckchem.com/pr....oducts/tbk1-IKKe-in-
hibitor group was significantly lower than that in DM group. According to qRT-PCR results, compared with those in Control group, mRNA expressions of Notch mRNA and miR-135a in the rat kidney tissues were substantially raised in DM group (p less then 0.05), and they were notably lowered in miR-13a inhibitor group compared with those in DM group (p less then 0.05). Finally, Western blotting results manifested that the protein levels of Notch, NIC, and Hes1 in the renal tissues of rats in DM group were considerably higher