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Consistent with hypotheses, gratitude uniquely predicted higher QoL beyond other predictors. In addition, gratitude buffered the effect of objective cognitive performance on QoL as expected, but did not interact with other predictors. These results suggest the need for further research into gratitude as a potential source of resilience for individuals with MS. (PsycInfo Database Record (c) 2020 APA, all rights reserved). These results suggest the need for further research into gratitude as a potential source of resilience for individuals