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Of Goal 3's nine targets, the two opioid crises hamper progress on Target 35, which aims at solidifying substance abuse prevention and treatment, including narcotic drug abuse, and Target 38, seeking to provide universal health coverage (UHC) and adequate access to essential medicines. Opioid crises, mirroring the mismatch between outmoded governmental structures and advancing scientific knowledge, share characteristics independent of the fundamental opioid compounds. Systemic weaknesses within regu