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In ccRCC, 58 lncRNAs and 660 mRNAs were determined to be differentially expressed. The optimal diagnostic lncRNAs for ccRCC included LINC02038, FAM242C, LINC01762, and PVT1, with PVT1 exhibiting a statistically significant association with patient survival. Gene Ontology (GO) analysis of cellular components demonstrated that differentially expressed messenger RNAs (DEmRNAs), which were co-expressed with four DElncRNAs,