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The purpose of this study was to assess the cortical-level sensory differences between natural teeth with a periodontal membrane and dental implants. We used functional near-infrared spectroscopy (fNIRS) to measure brain activity in the cerebral cortex of 12 patients who had both natural teeth and dental implants in the lower molar region. Painless ****y tactile stimulation was performed on both the natural teeth and the dental implants. Activation was seen in the somatosensory cortex during stimulation of both natural teeth and denta