https://www.selleckchem.com/pr....oducts/pf-3758309.ht
DNA ****tion checkpoint is a cell signaling pathway that is activated in response to perturbed ****tion. Although it is crucial for maintaining genomic integrity and cell survival, the exact mechanism of the checkpoint signaling remains to be understood. Emerging evidence has shown that RecQ helicases, a large family of helicases that are conserved from bacteria to yeasts and humans, contribute to the ****tion checkpoint as sensors, adaptors, or regulation targets. Here, we highlight the multiple functions of RecQ helicases
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