https://cm4620inhibitor.com/le....thal-neonatal-an-inf
Embryonic development is significantly influenced by Polycomb repressive complex 2 (PRC2), which suppresses gene transcription by modifying lysine 27 on histone H3 (H3K27). The catalytic subunit EZH2, part of the PRC2 core complex, is allosterically activated by EED upon the binding of trimethylated H3K27 (H3K27me3). The activation of mutations at Y641, A677, and A687 within the EZH2 enzymati
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