https://www.selleckchem.com/products/zen-3694.html
The anorectic effect of PYY makes it a potential pharmacological weight loss treatment. Modifications of the endogenous peptide to obtain commercially attractive pharmacological and biophysical stability properties are examined. Half-life extended PYY analogues were prepared and examined regarding Y -receptor potency as well as biophysical and stability properties. Deamidation of asparagine in position 18 and 29 was observed upon incubation at 37°C. Asparagine in position 18 - but not position 29 - could be substituted to glutamine wit
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