https://www.selleckchem.com/pr....oducts/geneticin-g41
Primary, secondary and tertiary structures of biosimilar Fraven® manufactured at both sites were found to be highly similar to the reference Neupogen®. Product related substances and impurities were also highly similar to the reference. Comparability of GCSF receptor binding affinities of each product was shown using the K values of SPR analysis. In vitro cell proliferation similarity was also evaluated and proven by PLA. Based on the similarity assessment, despite being manufactured at two different production sites, bio
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