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Our study comparing involvement patterns revealed that the ACTA1-NM cohort showed preferential sparing of the adductor and gracilis muscles. This is in contrast to the consistent tibialis posterior involvement in the TPM3-NM cohort and a unique MRI pattern when compared to other NM genotypes and congenital myopathies. Cases of foot drop were observed to be more frequently linked to a more pronounced involvement of the tibialis anterior muscle (P=0.002). The degree of tibialis anterior a