https://www.selleckchem.com/products/ms-275.html
While enhanced SERT function increased 5-HT receptor levels in OFC of Ala56 mice, RU24969-induced PPI deficits and hyperlocomotion were not different between genotypes. Baseline levels of cFos expression were not different between groups. RU24969 increased cFos expression in OFC of wild-types and decreased cFos in the striatum. While reducing 5-HT receptors may attenuate sensorimotor gating deficits, increased 5-HT levels in SERT Ala56 mice do not necessarily exacerbate these deficits, potentially due to compensations during neural circu
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