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RMR and measures of appetite were analyzed using a 2x2 (menopause status × CP/PL) repeated measures ANOVA. Significance was accepted at p≤0.05. RMR was significantly lower in postmenopausal compared to premenopausal women under both conditions (p=0.003). When consumed pre-sleep CP did not alter RMR, RER, or appetite compared to PL when assessed next-morning in pre and postmenopausal women. These data contribute to growing evidence that pre-sleep consumption of protein is not harmful to next-morning metabolism or appetite. In addition, these data demonstrate