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90%) was 62.1% lower than estimation based on the one-visit strategy (4.80%; 95% Cl = 4.68%, 4.93%). Similar results were found in the prevalence of hypertension (the one-visit 18.13% [17.34, 18.92]; the two-visit 9.47% [8.87, 10.07]). When the two-visit strategy was applied to the 2012-2015 China hypertension survey, the hypertension burden was predicted to be overestimated by 25.5%-47.8% (based on JNC 7) and 23.5%-48.2% (based on the 2017 ACC/AHA). CONCLUSION The hypertension burden would decrease from 244.5 million perso