https://www.selleckchem.com/pr....oducts/Rapamycin.htm
Antimicrobial use (AU) in days of therapy per 1000 patient-days (DOT/1000pd) varies widely among children's hospitals. We evaluated indirect standardization to adjust AU for case mix, a source of variation inadequately addressed by current measurements. Hospitalizations from the Pediatric Health Information System were grouped into 85 clinical strata. Observed to expected (OE) ratios were calculated by indirect standardization and compared to DOT/1000pd. Outliers were defined by OE z-scores. Antibacterial DOT/1000pd ranged from 345 to