https://www.selleckchem.com/pr....oducts/3-3-cgamp.htm
001). TRPM8 mRNA expression showed a significant positive association with abdominal pain scores (p=0.015). Treatment of IBS patient biopsies with icilin reduced release of inflammatory cytokines IL-1β, IL-6, and TNF-α (p0.05). These data indicate TRPM8 may have important anti-inflammatory properties and by this virtue can impact neuro-immune disease mechanisms in IBS. These data indicate TRPM8 may have important anti-inflammatory properties and by this virtue can impact neuro-immune disease mechanisms in IBS.Tissue-clearing techn
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